There are only three weeks remaining in the2025 NFL regular season.
TheLos Angeles Rams and Denver Broncosare the only teams to have clinched a playoff spot.
The Rams are currently the odds-on favorite to win Super Bowl 60. But the defending Super Bowl championPhiladelphia Eaglesmight have something to say about that.
In the AFC, theBuffalo Billshad a huge comeback win over the New England Patriots. Meanwhile, the Broncos are riding an 11-game winning streak.
There's still plenty left to settle with three weeks left in the regular season. Who is in best position for a trip to Santa Clara for Super Bowl 60? Here's an early look at some predictions and picks to win the AFC, NFC and which team will hoist the Lombardi Trophy in February.
AFC standings ahead of Week 16
Denver Broncos (12-2)
New England Patriots (11-3)
Jacksonville Jaguars (10-4)
Pittsburgh Steelers (8-6)
Los Angeles Chargers (10-4)
Buffalo Bills (10-4)
Houston Texans (9-5)
AFC Championship prediction:Billssurvive against Patriots
Josh Allen's passed for 3,276 yards and 25 touchdowns this season. He's the fourth player in NFL history with at least 3,000 passing yards and 25 touchdown passes in six of his first eight career seasons, per NFL Research. The Bills are too reliant on Allen, but I predict he'll have plenty of assistance against the Patriots in an all-AFC East championship game.
Running back James Cook produces over 130 yards from scrimmage and a touchdown. Buffalo's defense gets just enough stops as the Bills upset the Patriots in Foxborough again.
It'll mark Buffalo's first Super Bowl appearance since the 1993 season.
Take a look at the home stadiums for all 32 NFL teams
NFC standings ahead of Week 16
Los Angeles Rams (11-3)
Chicago Bears (10-4)
Philadelphia Eagles (9-5)
Tampa Bay Buccaneers (7-7)
Seattle Seahawks (11-3)
San Francisco 49ers (10-4)
Green Bay Packers (9-4-1)
NFC Championship prediction: Eagles hang on against Rams (again)
The Eagles had a get-right game against a badRaidersteam. I believe the Eagles finally find their groove during win-or-go-home situations in the postseason.
Philadelphia's offense has failed to establish an identity and struggled with consistency all season. But I predict they return to form with running backSaquon Barkleyleading the way.
Barkley ran all over the Rams in two meetings last season, but he was limited to 55 yards from scrimmage in a Week 3 win over Los Angeles.
The Eagles have won four straight games, including the playoffs, against the Rams dating back to 2023. The Rams' explosive offense will keep this game close, but Philly's overall talent on both sides of the ball prevails.
Super Bowl 60 prediction
Losers of four Super Bowls in a row in the early 90s, the Bills have a painful Super Bowl history. Unfortunately for Buffalo, Feb. 8 will add to the franchise's Super Bowl misery.
The Eagles have back-to-back standout performances to complete their title defense and win their second-straight Super Bowl.
Philadelphia's opportunistic defense forces two takeaways and the team scores 14 points off the turnovers.
Jalen Carter helps slow down Josh Allen, James Cook and the Bills offense. A.J. Brown produces more than 100 receiving yards and a touchdown, while Saquon Barkley compiles 100 yards on the ground against a leaky Buffalo defense.
All the drama surrounding the Eagles during the regular season becomes a thing of the past that galvanized the team to another Lombardi Trophy.
Super Bowl 60 odds breakdown
According to the current betting odds atBetMGM, the Los Angeles Rams have the best odds of winning Super Bowl 60 at +350.
NFL playoff schedule
Wild card round: Saturday, Jan. 10 to Monday, Jan. 12, 2026
Divisional round: Saturday, Jan. 17 to Sunday, Jan. 18, 2026
Conference championship: Sunday, Jan. 25, 2026
Super Bowl: Sunday, Feb. 8, 2026
Follow USA TODAY Sports' Tyler Dragon on X@TheTylerDragon.
This article originally appeared on USA TODAY:NFL Week 16 playoff predictions, Super Bowl prediction