Who Is Conan OBriens Wife, Liza Powel OBrien? All About the Comedian and Playwrights Longtime Marriage
Conan O'Brien's wife, Liza Powel O'Brien, was by his side when he received the Mark Twain Award for American Humor. Though the ceremony at the Kennedy Center took place in March 2025, the big moment in Conan's career began streaming on Netflix on May 4. Years before celebrating his special honor, Conan and Liza first met in 1999 while filming a remote segment for Late Night with Conan O'Brien at her advertising agency.
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